Searchable abstracts of presentations at key conferences in endocrinology

ea0049oc14.4 | Thyroid Cancer | ECE2017

Inverse relation between thyroid cancer incidence and threshold for thyroid surgery: a national population-based retrospective study

Decallonne Brigitte , den Bruel Annick Van , Nathalie Elaut , Schutter Harlinde De

Background: In Belgium, lower thyroid cancer incidence – most pronounced for microcancers (T1a) – is present in the North compared to the South. This variation is paralleled by differences in clinical practice: in the North less thyroid surgery is performed, more surgery is preceded by fine needle aspiration (FNA), and more patients with a final cancer diagnosis (2004–2006) underwent a presurgical FNA or a lymph node dissection (LND) at fist surgery.<p class...

ea0084ps2-06-47 | Hypothyroidism Treatment | ETA2022

Prescription of levothyroxine and concurrent use of anti-arrhythmic and bone-anti-resorptive drugs in belgium: retrospective study in a large population sample

Boets Liesbeth , Van Den Bruel Annick , Van Haecht Chris , Debbaut Bernard , Ntahonganyira Rose-Marie , Cornelis Koen , Stokx Jocelijn , Decallonne Brigitte

Background and objective: Increased prescription of levothyroxine (LT4) has been observed in the USA and countries in Europe and has been related to increased thyroid function screening and a lower treatment threshold, increasing risk for overdiagnosis and overtreatment. We wanted to study the evolution of LT4 prescriptions in Belgium, and compare the use of anti-arrhythmic drugs (AAD) and bone-anti-resorptive drugs (BAD) between LT4-users and non-LT4-users.<p class="abste...

ea0088013 | Abstracts | BES2022

TPO antibody status prior to first radioactive iodine therapy as a predictive parameter for hypothyroidism in Graves’ disease

Sebastien Verdickt , Nes Falco Van , Carolien Moyson , Toon Maes , Crombrugge Paul Van , den Bruel Annick Van , Brigitte Decallonne

Objective: We investigated if a positive thyroid peroxidase antibody (TPO Ab) status before radioactive iodine (RAI) therapy in patients with Graves’ hyperthyroidism is a predictive factor for developing hypothyroidism after RAI.Methods: We performed a retrospective study of patients with Graves’ hyperthyroidism with known TPO Ab status, receiving a first administration of RAI. Patients from 4 thyroid outpatient centres in Belgium receiving a f...

ea0079007 | Abstracts | BES2021

Fasting plasma glucose level to determine the need for an OGTT to screen for gestational diabetes mellitus

Kaat Beunen , Astrid Neys , Paul Van Crombrugge , Carolien Moyson , Johan Verhaeghe , Sofie Vandeginste , Hilde Verlaenen , Chris Vercammen , Toon Maes , Els Dufraimont , Christophe De Block , Yves Jacquemyn , Farah Mekahli , Katrien De Clippel , Den Bruel Annick Van , Anne Loccufier , Annouschka Laenen , Roland Devlieger , Chantal Mathieu , Katrien Benhalima

Aims: To determine the fasting plasma glucose (FPG) level at which an oral glucose tolerance test (OGTT) could be avoided to screen for gestational diabetes (GDM) and to evaluate the characteristics of women across this FPG threshold.Methods: A multi-centric prospective cohort study (BEDIP-N) with 1843 women receiving screening for GDM with a 75g OGTT.Results: A FPG < 78 mg/dl was the FPG cut-off with the best trade-off to limi...

ea0079016 | Abstracts | BES2021

Characteristics, pregnancy outcomes and tolerance of screening tests according to the preference of women for the method of GDM screening

Lore Raets , Marie Vandewinkel , Paul Van Crombrugge , Carolien Moyson , Johan Verhaeghe , Sofie Vandeginste , Hilde Verlaenen , Chris Vercammen , Toon Maes , Els Dufraimont , Block Christophe De , Yves Jacquemyn , Farah Mekahli , Katrien De Clippel , Den Bruel Annick Van , Anne Loccufier , Annouschka Laenen , Roland Devlieger , Chantal Mathieu , Katrien Benhalima

Aims: To compare the characteristics, pregnancy outcomes and tolerance of screening tests between women who prefer a two-step screening strategy with a glucose challenge test (GCT), women who prefer an one-step screening strategy with an oral glucose tolerance test (OGTT) and women without clear preference for screening method for gestational diabetes mellitus (GDM). Methods: 1803 women from a Belgian multi-centric prospective cohort study (BEDIP-N study...

ea0084ps3-13-115 | Pregnancy & Iodine | ETA2022

Higher thyroid FT3-to-FT4 ratio is associated with gestational diabetes mellitus and adverse pregnancy outcomes

Raets Lore , Minschart Caro , Van Den Bruel Annick , Van en Bogaert Emmelien , Van Crombrugge Paul , Moyson Carolien , Verhaeghe Johan , Vandeginste Sofie , Verlaenen Hilde , Vercammen Chris , Maes Toon , Dufraimont Els , Roggen Nele , De Block Christophe , Jacquemyn Yves , Mekahli Farah , De Clippel Katrien , Loccufier Anne , Laenen Annouschka , Devlieger Roland , Mathieu Chantal , Decallonne Brigitte , Benhalima Katrien

Aim: To determine the association between thyroid function and the risk for gestational diabetes mellitus (GDM) and adverse pregnancy outcomes.Methods: This case-control study was a sub-analysis of the BEDIP-N study, in which 199 GDM women were matched for age and body mass index with 398 controls. Thyroid stimulating hormone (TSH), free thyroxine (fT4), free triiodothyronine (fT3), and thyroid peroxidase (TPO) antibodies were measured at 6-14 weeks and ...